Enamel-like tissue regeneration by using biomimetic enamel matrix proteins
نویسندگان
چکیده
منابع مشابه
Enamel matrix proteins in the
Aim: This prospective multicentre randomized controlled clinical trial was designed to compare the clinical outcomes of papilla preservation flap surgery with or without the application of enamel matrix proteins (EMD). Material and methods: 172 patients with advanced chronic periodontitis were recruited in 12 centers in 7 countries. All patients had at least one intrabony defect of >3mm. Heavy ...
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O ne way to attempt periodontal regeneration is to mimic the biologic processes involved in nascent tooth development, especially the development of the root and the supporting tissues. The EMDOGAIN® (BIORA AB, Malmö, Sweden) concept is based on the discovery that enamel matrix proteins are not only involved in enamel formation but also play a key role in the formation of acellular cementum [1,...
متن کاملEnamel matrix protein derivatives: role in periodontal regeneration
The role of regenerative periodontal therapy is the reconstitution of lost periodontal structures, ie, new formation of root cementum, periodontal ligament, and alveolar bone. The outcome of basic research has pointed to the important role of enamel matrix protein derivative (EMD) in periodontal wound healing. Histologic results from animal and human studies have shown that treatment with EMD p...
متن کاملRole of macromolecular assembly of enamel matrix proteins in enamel formation.
Unlike other mineralized tissues, mature dental enamel is primarily (> 95% by weight) composed of apatitic crystals and has a unique hierarchical structure. Due to its high mineral content and organized structure, enamel has exceptional functional properties and is the hardest substance in the human body. Enamel formation (amelogenesis) is the result of highly orchestrated extracellular process...
متن کاملEnamel matrix derivative for periodontal tissue regeneration in treatment of intrabony defects: a Cochrane systematic review.
We reviewed the literature on the efficacy of enamel matrix derivative (EMD) in comparison with open flap debridement, guided tissue regeneration (GTR), and bone grafting for the treatment of intrabony defects. We searched four major electronic databases for randomized controlled trials (RCTs) with at least one year of follow-up. Several journals were handsearched with no language restrictions....
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ژورنال
عنوان ژورنال: International Journal of Biological Macromolecules
سال: 2021
ISSN: 0141-8130
DOI: 10.1016/j.ijbiomac.2021.06.028